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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIRAP All Species: 11.52
Human Site: S62 Identified Species: 31.67
UniProt: P58753 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58753 NP_001034750.1 221 23883 S62 S P L P P S L S S V T S P S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta NP_001123907 220 24019 S61 D R L S P S L S L V T S P S L
Dog Lupus familis XP_851910 435 46698 S276 L G L S S A V S P N S P S T Y
Cat Felis silvestris
Mouse Mus musculus Q99JY1 241 26017 G82 S P S S C S S G M S P T S P P
Rat Rattus norvegicus XP_001055833 250 26813 M91 T P S C S S G M S P T S P P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514911 373 39387 S132 A P S V S R S S L P S Q E P S
Chicken Gallus gallus NP_001020000 221 24806 S67 R P A P V D I S S S S S A R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922965 226 25971 S65 L P S F L S S S L R S A L K Y
Tiger Blowfish Takifugu rubipres NP_001106667 180 20118 S27 S F C P L S S S W T P T V P Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.2 42.7 N.A. 73.4 70.8 N.A. 35.9 45.7 N.A. 38 34.3 N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 95.9 46.9 N.A. 78.8 76.8 N.A. 45.3 59.7 N.A. 53.9 44.8 N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 73.3 13.3 N.A. 20 40 N.A. 13.3 33.3 N.A. 20 26.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 73.3 40 N.A. 26.6 46.6 N.A. 26.6 46.6 N.A. 33.3 33.3 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 12 0 0 12 0 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 12 12 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 12 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % K
% Leu: 23 0 34 0 23 0 23 0 34 0 0 0 12 0 23 % L
% Met: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 67 0 34 23 0 0 0 12 23 23 12 34 45 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 12 % Q
% Arg: 12 12 0 0 0 12 0 0 0 12 0 0 0 12 0 % R
% Ser: 34 0 45 34 34 67 45 78 34 23 45 45 23 23 12 % S
% Thr: 12 0 0 0 0 0 0 0 0 12 34 23 0 12 12 % T
% Val: 0 0 0 12 12 0 12 0 0 23 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _